- Before You Start
- Illumina HT DNA sequencing equipment
- cBot Cluster Generation System
- Covaris S220 Focused Acoustic Shearer
- Agilent Bioanalyzer Equipment
- Nanodrop Quantification Equipment
- Speed-Vac Concentrator System
- Array Automation's ArrayPlex - Automated/Robotic Instrumentation
- Affymetrix microarrays equipment
- PacBio RS
- Fluidigm C1
- BioNano Irys
Bioinformatics Core Overview
The goal of the Genomics High-Throughput Facility (GHTF) is to provide clients with the resources required to carry out their large-scale genomics experiments. Bioinformatics support is available to support experiments using the high-throughput sequencers and Affymetrix expression arrays.
The Bioinformatics Core of the GHTF relies on the support from several UCI units, including:
- The Institute for Genomics and Bioinformatics (IGB)
- The Chao Family Comprehensive Cancer Center (CFCCC)
- The UCI Office of Research Computing Support (RCS)
- The UCI Institute for Clinical and Translational Science (ICTS)
The Genomics High-Throughput Facility offers a range of bioinformatics services to its clients. Bioinformatics support is available for the full experimental process, as the data are generated in the laboratory through the tertiary statistical analysis of the data. The following figure shows an overview of the Bioinformatics Core components.
The major components of the Bioinformatics Core include:
- The IGB Sequence Data Pipeline
- Free computation resources
- Free and commercial software for bioinformatics and statistical analysis
- Collaboration opportunities with UCI faculty
- Service for grant writing for CFCCC members
- Consulting services for secondary through tertiary stages of data analysis
The Bioinformatics Core has expertise in all experimental designs utilizing high-throughput sequencers and Affymetrixs expression arrays. GHTF clients are encouraged to contact the Bioinformatics Core at the planning stage of their high-throughput experiments to ensure that the bioinformatics requirements of the study are available.
Inquiries should be directed to:
Dr. Jenny Wu
Chao Family Comprehensive Cancer Center
The Institute is led by Director Pierre Baldi, of the Donald Bren School of Information and Computer Sciences, and Associate Director Suzanne Sandmeyer of the School of Medicine. The Director and Associate Director are supported by nine core Program Area Leaders, representing the breadth of IGB inquiry. These research areas are Biochemical Engineering, Chemical Biology, Drug Discovery, Evolutionary Genomics, Medical Informatics, Functional Genomics, Disease Genomics, Structural Genomics and Systems Biology. The Institute for Genomics and Bioinformatics provides consultation and collaborative bioinformatics services.
Located on the UC Irvine Medical Centercampus, the Chao Family Comprehensive Cancer Center is affiliated with the School of Medicine at the University of California, Irvine. As a university facility, the cancer center offers the expertise of a scientific community that is internationally renowned for its work in the prevention, diagnosis and treatment of cancer. Chao Family Comprehensive Cancer Center, Orange County's only National Cancer Institute-designated comprehensive cancer center, is committed to providing the most comprehensive patient care possible with its world-class multidisciplinary team. By combining the efforts of researchers, surgeons, radiation oncologists, medical oncologists, pathologists, nurses, rehabilitation therapists, pharmacists, social workers and dietitians, the cancer center addresses the disease on all levels.