The mission of the UCI Genomics High-Throughput Facility (GHTF) is to provide genome-wide analysis for clients interested in gene expression, regulation of gene expression, and genome sequence and variation. The primary forms of genome-wide analysis are the Affymetrix GeneChip and Illumina HiSeq 2000 next generation sequencing. The GHTF (previously UCI DNA & Protein MicroArray Facility) was established in 1999 as a shared resource, affiliated with the Chao Family Comprehensive Cancer Center, an NCI-designated Comprehensive Cancer Center, with the goal of assisting UCI Campus and Medical Center investigators. The shared resource has expanded and currently provides services to numerous outside academic, non-profit institutions and commercial biotech entities.

In addition to providing experimental expertise for performing microarray and high-throughput DNA sequencing, the staff provides advice and consultation on experimental design, general analysis approaches and statistics for microarray and high-throughput DNA sequencing-based research.